What is a common side effect of statin medications?

Muscle pain or weakness is a well-documented and common side effect associated with statin medications, which are primarily used to lower cholesterol levels and reduce cardiovascular disease risk. This side effect, often referred to as statin-associated muscle symptoms (SAMS), can vary in severity from mild discomfort to significant pain that may interfere with daily activities. The exact mechanism behind this side effect is not fully understood, but it is believed to be related to the impact statins have on muscle metabolism and energy production.

Other potential side effects of statins may include liver enzyme abnormalities or gastrointestinal symptoms, but muscle pain or weakness is particularly prominent in clinical observations and patient reports. Recognizing this side effect is crucial for healthcare providers, as they may need to reassess the treatment regimen if patients experience significant muscle-related symptoms. This helps ensure patient adherence to therapy and overall satisfaction with their care.