What type of reaction is a patient at risk for when using corticosteroids?

Corticosteroids are known to be associated with Type C reactions, also referred to as chronic effects or dose-related adverse reactions. These reactions occur as a result of the pharmacological properties of the drug and the way it interacts with the body over time or at certain dosages.

Long-term use of corticosteroids can lead to a variety of predictable side effects due to their mechanism of action, which includes immunosuppression, alterations in glucose metabolism, weight gain, osteoporosis, and adrenal suppression. The effects are typically related to the dosage and duration of therapy, making them identifiable and somewhat manageable through appropriate monitoring and adjustments in therapy.

Understanding that corticosteroids can lead to a range of cumulative and dose-dependent effects is crucial in therapeutic decision-making and patient education. Awareness of Type C reactions can help prescribers implement preventive strategies, such as using alternate-day therapy or prophylactic measures to mitigate risks like osteoporosis.