Which of the following are potential side effects of montelukast (Singulair)?

Montelukast, commonly known by its brand name Singulair, is a leukotriene receptor antagonist used primarily for the management of asthma and allergic rhinitis. Among its potential side effects, the association with psychological effects such as aggression, anxiety, depression, and suicidal thoughts has been noted. These side effects can occur as montelukast works on the leukotriene pathways, which are believed to play a role in mood regulation and neurobehaviors.

The recognition of these psychological side effects has led to warnings issued by health authorities, emphasizing the need for healthcare providers to monitor patients closely for any changes in mood or behavior after starting treatment. Patients and caregivers are advised to report any such symptoms promptly to their prescriber.

While montelukast can have other side effects, including gastrointestinal issues or somnolence, the specific link to aggression and mood disturbances underscores the importance of weighty considerations regarding mental health when evaluating treatment options. This understanding is crucial for healthcare providers when prescribing this medication and discussing its benefits and risks with patients.